INX-189 clinical attrition - a call for re-look at single isomer strategy of Gilead?

October 2012

Discussion posted Pharmaceutical Discussion Group on LinkedIn

http://www.linkedin.com/groups/INX-189-clinical-attrition-call-38263.S.156348010?goback=%2Egde_38263_member_103345417

Is the purported toxicity of the non-active diastereoisomer in a P-chiral nucleotide prodrug (protide) a scientifically derived hypothesis OR is it merely a surmise from a coincidence that no active-isomer is found toxic till date? (considering very few 'single isomers' entered PI till date..)

The quintessential 'Indian vegetarian meal' prototype on Emirates

23 Nov 2012

On FB McKinsey article "the trouble with Travel distribution" 

http://www.facebook.com/mckinseyquarterly/posts/432757166778183

Yes indeed - the globe trotting traveler these days can negotiate and get deals on anything & everything, except if he/she's an Indian vegetarian, flying any global airlines and hoping for a gourmet food experience.... Get real chum, eat ur paneer, okhra, rice & all together :-l